Eye colour: portals into pigmentation genes and ancestry

被引:109
作者
Sturm, RA [1 ]
Frudakis, TN
机构
[1] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia
[2] DNAPrint Genomics Inc, Sarasota, FL 34236 USA
关键词
D O I
10.1016/j.tig.2004.06.010
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Several recent papers have tried to address the genetic determination of eye colour via microsatellite linkage, testing of pigmentation candidate gene polymorphisms and the genome wide analysis of SNP markers that are informative for ancestry. These studies show that the OCA2 gene on chromosome 15 is the major determinant of brown and/or blue eye colour but also indicate that other loci will be involved in the broad range of hues seen in this trait in Europeans.
引用
收藏
页码:327 / 332
页数:6
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