Detecting RNA and DNA with templated chemical reactions

被引：224

作者：

Silverman, Adam P. ^{[1
]}

Kool, Eric T. ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

CHEMICAL REVIEWS | 2006年 / 106卷 / 09期

关键词：

D O I：

10.1021/cr050057+

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review covers recent advances in the development of chemical reactions that are triggered by hybridization of an oligonucleotide to a target ribonucleic acid (RNA) or deoxyribonucleic acid (DNA) strand. It is shown how these reactions are being used, or could be used, in detecting and identifying such targets in a biological sample or cell. First, the basic principles of DNA and RNA molecular recognition that underlie this research are discussed. Second, the historical development of such templated reactions is outlined and the current state of the art delineated. Finally, future areas of special promise are predicted.

引用

页码：3775 / 3789

页数：15

共 197 条

[1] Flow cytometric detection of specific RNAs in native human cells with quenched autoligating FRET probes [J].

Abe, H ;

Kool, ET .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (02) :263-268

[2] Destabilizing universal linkers for signal amplification in self-ligating probes for RNA [J].

Abe, H ;

Kool, ET .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (43) :13980-13986

[3] DETECTION OF POINT MUTATIONS WITH A MODIFIED LIGASE CHAIN-REACTION (GAP-LCR) [J].

ABRAVAYA, K ;

CARRINO, JJ ;

MULDOON, S ;

LEE, HH .

NUCLEIC ACIDS RESEARCH, 1995, 23 (04) :675-682

[4] DNA duplex-quadruplex exchange as the basis for a nanomolecular machine [J].

Alberti, P ;

Mergny, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (04) :1569-1573

[5] CHEMICAL SYNTHESIS OF OLIGODEOXYNUCLEOTIDE DUMBBELLS [J].

ASHLEY, GW ;

KUSHLAN, DM .

BIOCHEMISTRY, 1991, 30 (11) :2927-2933

[6] GENETIC-DISEASE DETECTION AND DNA AMPLIFICATION USING CLONED THERMOSTABLE LIGASE [J].

BARANY, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (01) :189-193

[7] SEQUENCE-SPECIFIC CLEAVAGE OF HIV MESSENGER-RNA BY A RIBOZYME MIMIC [J].

BASHKIN, JK ;

FROLOVA, EI ;

SAMPATH, US .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (13) :5981-5982

[8] Building blocks for ribozyme mimics: Conjugates of terpyridine and bipyridine with nucleosides [J].

Bashkin, JK ;

Xie, J ;

Daniher, AT ;

Sampath, U ;

Kao, JLF .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (07) :2314-2321

[9] THE FUNCTIONALIZATION OF OLIGONUCLEOTIDES VIA PHOSPHORAMIDITE DERIVATIVES [J].

BEAUCAGE, SL ;

IYER, RP .

TETRAHEDRON, 1993, 49 (10) :1925-1963

[10] PRECISION SEQUENCE-SPECIFIC CLEAVAGE OF A NUCLEIC-ACID BY A MINOR-GROOVE-DIRECTED METAL-BINDING LIGAND LINKED THROUGH N-2 OF DEOXYGUANOSINE [J].

BERGSTROM, DE ;

GERRY, NP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (26) :12067-12068

← 1 2 3 4 5 6 7 8 9 10 →