Effectiveness of sotalol treatment in symptomatic Brugada syndrome

被引：15

作者：

Glatter, KA

Wang, Q

Keating, M

Chen, SH

Chiamvimonvat, N

Scheinman, MM

机构：

[1] Univ Calif Davis, Dept Cardiol ACC, Sacramento, CA 95817 USA

[2] Univ Calif San Francisco, San Francisco, CA 94143 USA

[3] Case Western Reserve Univ, Ctr Cardiovasc Genet, Dept Mol Cardiol, Cleveland, OH 44106 USA

[4] Case Western Reserve Univ, Dept Mol Med, Cleveland Clin Fdn, Cleveland, OH 44106 USA

[5] Case Western Reserve Univ, Cleveland Clin Coll Med, Cleveland, OH 44106 USA

[6] Boston Childrens Hosp, Boston, MA USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2004年 / 93卷 / 10期

关键词：

D O I：

10.1016/j.amjcard.2004.02.023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a 53-year-old man with recurrent syncopal events and a malignant family history who was treated for 13 years with sotalol drug therapy with no further occurrence of Brugada syndrome symptoms. Genetic testing revealed that he carried a Brugada syndrome sodium channel SCN5A mutation (4189delT). This finding suggests that sotalol may be of therapeutic benefit in such patients. (C) 2004,by Excerpta Medica, Inc.

引用

页码：1320 / 1322

页数：3

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