Experiments carried out under flat smooth bed condition in a periodic, asymmetric, Kinoshita meandering channel showed that bend skewness controls the three-dimensional mean flow (e. g., primary and secondary flow) and turbulence structure (e. g., location of shear layers and turbulent shear stresses). In this paper, similar hydraulic conditions are used to perform movable-bed experiments with uniform sediment size in order to study the effect of bend orientation on bed morphodynamics. Two main differences between the upstream- and downstream-skewed meander configurations are found: (1) for the case of bends oriented upstream valley, the bed forms are produced just upstream of the bend apex, whereas for the case of bends oriented downstream valley they are observed around the upstream inflection point, and (2) the downstream-skewed condition produces the deepest scour region, which is located downstream of the bend apex. A comparison with observations at two bends on the Wabash River, Illinois, shows some remarkable similarities with the bed morphology observed in the Kinoshita channel. Further analysis of the bed form celerity, bed load transport during evolution, and superimposition of migrating bed forms and their implications on bend migration are presented.