Age and gender effects on serotonin-dependent plasticity in respiratory motor control

被引：72

作者：

Behan, M ^{[1
]}

Zabka, AG ^{[1
]}

Mitchell, GS ^{[1
]}

机构：

[1] Univ Wisconsin, Sch Vet Med, Dept Comparat Biosci, Madison, WI 53706 USA

来源：

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY | 2002年 / 131卷 / 1-2期

关键词：

control of breathing; plasticity; development; age; hypoxia; long-term-facilitation; mammals; rat; seroton-independent; gender;

D O I：

10.1016/S1569-9048(02)00038-1

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

We review recent evidence indicating that serotonin-dependent plasticity in respiratory control is influenced by age and gender. Specifically, respiratory long-term-facilitation following intermittent hypoxia decreases with age in male rats, but increases in female rats. We speculate about a possible relationship between age and gender effects oil serotonin-dependent plasticity in upper airway motoneuron pools and the prevalence of obstructive sleep apnea. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：65 / 77

页数：13

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