Fluorinated fatty acids: New mechanistic probes for desaturases

被引：13

作者：

Buist, PH ^{[1
]}

Behrouzian, B ^{[1
]}

Alexopoulos, KA ^{[1
]}

Dawson, B ^{[1
]}

Black, B ^{[1
]}

机构：

[1] HLTH CANADA,HLTH PROTECT BRANCH,DRUGS DIRECTORATE,BUR DRUG RES,OTTAWA,ON K1A 0L2,CANADA

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 23期

关键词：

D O I：

10.1039/cc9960002671

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Only (E)-fluoroalkenic products are obtained when racemic 9- and 10-fluoro fatty acids are processed by a Saccharomyces cerevisiae Delta 9 desaturase as determined by H-1-decoupled F-19 NMR and GC-MS analysis; no evidence for hydroxylated intermediates was found.

引用

页码：2671 / 2672

页数：2

共 14 条

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