Dynamics and configurational fluctuations of single DNA molecules in linear mixed flows

被引:73
作者
Hur, JS [1 ]
Shaqfeh, ESG
Babcock, HP
Chu, S
机构
[1] Stanford Univ, Dept Chem Engn, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Chem & Mech Engn, Stanford, CA 94305 USA
[3] Stanford Univ, Dept Phys & Appl Phys, Stanford, CA 94305 USA
来源
PHYSICAL REVIEW E | 2002年 / 66卷 / 01期
关键词
D O I
10.1103/PhysRevE.66.011915
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We examine the dynamics of DNA molecules in mixed flows where the ratio of vorticity to strain rate may be slightly above or below unity via Brownian dynamics simulation. We find that the chain dynamics in these flows are dramatically different than those found for simple shear flow. When the strain rate exceeds vorticity, the dynamics are found to be driven by the extra amount of straining. For vorticity-dominated flows, a periodicity in chain extension is observed with considerable chain deformation.
引用
收藏
页码:1 / 011915
页数:4
相关论文
共 39 条
[1]   Effect of initial conformation, flow strength, and hydrodynamic interaction on polymer molecules in extensional flows [J].
Agarwal, US .
JOURNAL OF CHEMICAL PHYSICS, 2000, 113 (08) :3397-3403
[2]   Relating the microscopic and macroscopic response of a polymeric fluid in a shearing flow [J].
Babcock, HP ;
Smith, DE ;
Hur, JS ;
Shaqfeh, ESG ;
Chu, S .
PHYSICAL REVIEW LETTERS, 2000, 85 (09) :2018-2021
[3]  
BABCOCK HP, UNPUB
[4]   BLOCK COPOLYMER THERMODYNAMICS - THEORY AND EXPERIMENT [J].
BATES, FS ;
FREDRICKSON, GH .
ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 1990, 41 (01) :525-557
[5]  
Bird R.B., 1987, DYNAMICS POLYM LIQUI, V2
[6]   COIL-STRETCH TRANSITION OF DILUTE FLEXIBLE POLYMERS UNDER ULTRAHIGH VELOCITY-GRADIENTS [J].
DEGENNES, PG .
JOURNAL OF CHEMICAL PHYSICS, 1974, 60 (12) :5030-5042
[7]  
Doi M., 1986, The Theory of Polymer Dynamics
[8]   Dynamic simulation of freely draining flexible polymers in steady linear flows [J].
Doyle, PS ;
Shaqfeh, ESG ;
Gast, AP .
JOURNAL OF FLUID MECHANICS, 1997, 334 :251-291
[9]   Effects of stiffness on the flow behavior of polymers [J].
Dua, A ;
Cherayil, BJ .
JOURNAL OF CHEMICAL PHYSICS, 2000, 113 (23) :10776-10783
[10]   Chain dynamics in steady shear flow [J].
Dua, A ;
Cherayil, BJ .
JOURNAL OF CHEMICAL PHYSICS, 2000, 112 (19) :8707-8714