Seronegative infection and AIDS caused by an A2 subsubtype HIV-1

被引：11

作者：

Cardoso, AR ^{[1
]}

Gonçalves, C

Pascoalinho, D

Gil, C

Ferreira, AF

Bártolo, I

Taveira, N

机构：

[1] Hosp Nossa Senhora Graca, Tomar, Portugal

[2] Fac Farm Lisboa, Ctr Patogenese Mol, Lisbon, Portugal

[3] Inst Super Ciencias Saude Sul, Caparica, Portugal

来源：

AIDS | 2004年 / 18卷 / 07期

关键词：

D O I：

10.1097/00002030-200404300-00018

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The study of true seronegative HIV-1 infections may have important implications for the diagnosis and prevention of HIV-1 infection. The case of an AIDS patient with persistently negative HIV serology is described. Genetic and phylogenetic analysis indicated that she was infected with an A2 subsubtype HIV-1 transmitted by her seropositive and asymptomatic sexual partner. The clinical and serological discordant results suggest the presence of an immunological deficiency that prevents the formation of HIV-1-specific antibodies.

引用

页码：1071 / 1074

页数：4

共 17 条

[1] Evaluation of the clinical sensitivities of three viral load assays with plasma samples from a pediatric population predominantly infected with human immunodeficiency virus type 1 subtype G and BG recombinant forms [J].