Synthesis of well-defined hydrogel networks using Click chemistry

被引:444
作者
Malkoch, Michael
Vestberg, Robert
Gupta, Nalini
Mespouille, Laetitia
Dubois, Philipe
Mason, Andrew F.
Hedrick, James L.
Liao, Qi
Frank, Curtis W.
Kingsbury, Kevin
Hawker, Craig J.
机构
[1] IBM Almaden Res Ctr, San Jose, CA 95120 USA
[2] Univ Calif Santa Barbara, Mat Res Lab, Santa Barbara, CA 93106 USA
[3] Univ Mons, LPCM, B-7000 Mons, Belgium
[4] Stanford Univ, Dept Chem Engn, Stanford, CA 94305 USA
[5] Calif Polytech State Univ San Luis Obispo, Dept Chem & Biochem, San Luis Obispo, CA 93407 USA
关键词
D O I
10.1039/b603438a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
New PEG-based hydrogel materials have been synthesized by Click chemistry and shown to result in well-defined networks having significantly improved mechanical properties; the selectivity of the azide/ acetylene coupling reaction also allows for the incorporation of various additives and functional groups leading to chemical tailoring of the hydrogels.
引用
收藏
页码:2774 / 2776
页数:3
相关论文
共 29 条
[1]   Click chemistry in materials synthesis.: 1.: Adhesive polymers from copper-catalyzed azide-alkyne cycloaddition [J].
Díaz, DD ;
Punna, S ;
Holzer, P ;
Mcpherson, AK ;
Sharpless, KB ;
Fokin, VV ;
Finn, MG .
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2004, 42 (17) :4392-4403
[2]   Ideal tetrafunctional amphiphilic PEG/PDMS conetworks by a dual-purpose extender/crosslinker. I. Synthesis [J].
Erdodi, G ;
Kennedy, JP .
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2005, 43 (20) :4953-4964
[3]   Hyperbranched fluoropolymer and linear poly(ethylene glycol) based Amphiphilic crosslinked networks as efficient antifouling coatings: An insight into the surface compositions, topographies, and morphologies [J].
Gudipati, CS ;
Greenlief, CM ;
Johnson, JA ;
Prayongpan, P ;
Wooley, KL .
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2004, 42 (24) :6193-6208
[4]   Synthesis and characterization of novel biodegradable unsaturated poly(ester amide)/poly(ethylene glycol) diacrylate hydrogels [J].
Guo, K ;
Chu, CC .
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2005, 43 (17) :3932-3944
[5]   Light-activated hydrogel formation via the triggered folding and self-assembly of a designed peptide [J].
Haines, LA ;
Rajagopal, K ;
Ozbas, B ;
Salick, DA ;
Pochan, DJ ;
Schneider, JP .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (48) :17025-17029
[6]   The convergence of synthetic organic and polymer chemistries [J].
Hawker, CJ ;
Wooley, KL .
SCIENCE, 2005, 309 (5738) :1200-1205
[7]   Dendronized linear polymers via "click chemistry" [J].
Helms, B ;
Mynar, JL ;
Hawker, CJ ;
Fréchet, JMJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (46) :15020-15021
[8]   Fast and convenient divergent synthesis of aliphatic ester dendrimers by anhydride coupling [J].
Ihre, H ;
De Jesús, OLP ;
Fréchet, JMJ .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (25) :5908-5917
[9]   Mechanically strong hydrogels with ultra-low frictional coefficients [J].
Kaneko, D ;
Tada, T ;
Kurokawa, T ;
Gong, JP ;
Osada, Y .
ADVANCED MATERIALS, 2005, 17 (05) :535-+
[10]   Hydrogels for tissue engineering [J].
Lee, KY ;
Mooney, DJ .
CHEMICAL REVIEWS, 2001, 101 (07) :1869-1879