Amyloid plus Activation = Alzheimer's?

被引：11

作者：

Jagust, William ^{[1
]}

机构：

[1] Univ Calif Berkeley, Helen Wills Neurosci Inst, Berkeley, CA 94720 USA

来源：

NEURON | 2009年 / 63卷 / 02期

关键词：

GENETIC RISK; DISEASE; MEMORY; IMPAIRMENT; NETWORK; PEOPLE; MRI;

D O I：

10.1016/j.neuron.2009.07.008

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

PET imaging of Alzheimer's disease (AD) patients demonstrates A beta-protein accumulation in a default mode network. In this issue of Neuron, Sperling and colleagues show that cognitively intact individuals with A beta in this network fail to deactivate it during memory tasks, a finding with important implications for cognitive aging and early detection of AD.

引用

页码：141 / 143

页数：3

共 15 条

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