Infectious and inflammatory mechanisms in preterm birth and cerebral palsy

被引:28
作者
Jacobsson, B [1 ]
机构
[1] Univ Gothenburg, Sahlgrenska Acad, Inst Hlth Women & Children, Dept Obstet & Gynecol,Perinatal Ctr, SE-41685 Gothenburg, Sweden
来源
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2004年 / 115卷 / 02期
关键词
preterm birth; preterm labor; preterm-prelabor rupture of membranes; intra-uterine infection; intra-ammotic inflammation; interleukin-6; interleukin-8; interleukin-18; monocyte chernotactic protein-1; cerebral palsy; antenatal risk factors; chorioamnionitis;
D O I
10.1016/j.ejogrb.2003.11.014
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: In a thesis examine infectious and inflammatory mechanisms involved in preterm birth and cerebral palsy. Study design: Four cross-sectional studies and a case control study. Results: Microbial invasion of the amniotic cavity and inflammation in this population of Swedish women in preterm labor and preterm prelabor rupture of membranes was similar to that reported in data from populations with a higher incidence of preterm birth. Our data support an association between antenatal infection/inflammation and cerebral palsy. Conclusions: Infectious and inflammatory mechanisms are involved in preterm birth and cerebral palsy in a population with low incidence of preterm birth. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:159 / 160
页数:2
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