Proteomics of breast cancer - Principles and potential clinical applications

被引：59

作者：

Bertucci, Francois

Birnbaum, Daniel

Goncalves, Anthony

机构：

[1] Inst J Paoli I Calmettes, Dept Mol Oncol, Ctr Rech Cancerol Marseille, F-13009 Marseille, France

[2] Univ Mediterranee, Fac Med, F-13009 Marseille, France

[3] Univ Mediterranee, Dept Med Oncol, F-13009 Marseille, France

[4] Univ Mediterranee, IPC, Dept Mol Pharmacol, F-13009 Marseille, France

来源：

MOLECULAR & CELLULAR PROTEOMICS | 2006年 / 5卷 / 10期

关键词：

D O I：

10.1074/mcp.R600011-MCP200

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Progresses in screening, early diagnosis, prediction of aggressiveness and of therapeutic response or toxicity, and identification of new targets for therapeutic will improve survival of breast cancer. These progresses will likely be accelerated by the new proteomic techniques. In this review, we describe the different techniques currently applied to clinical samples of breast cancer and the most important results obtained with the two most popular proteomic approaches in translational research (tissue microarrays and SELDI-TOF).

引用

页码：1772 / 1786

页数：15

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