A new monoterpene glycoside and antibacterial monoterpene glycosides from Paeonia suffruticosa

被引：47

作者：

An, Ren-Bo

Kim, Hyun-Chul

Lee, Sung-Hee

Jeong, Gil-Saeng

Sohn, Dong-Hwan

Park, Hyun

Kwon, Dong-Yeul

Lee, John Hwa

Kim, Youn-Chul

机构：

[1] Wonkwang Univ, Coll Pharm, Iksan 570749, Jeonbuk, South Korea

[2] Yanbian Univ, Coll Pharm, Jilin 133000, Peoples R China

[3] Wonkwang Univ, Coll Med, Dept Infect Biol, Iksan 570749, South Korea

[4] Chonbuk Natl Univ, Coll Vet Med & Biosafety Res Inst, Chonju 561756, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2006年 / 29卷 / 10期

关键词：

Paeonia suffruticosa; 6-O-vanillyoxypaeoniflorin; monoterpene glycoside; mudanpioside-H; galloyl-oxypaeoniflorin; antibacterial;

D O I：

10.1007/BF02973899

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Antibacterial activity-guided fractionation of the CHCl3-MeOH (1:1) extract of Paeonia suffruti-cosa root bark furnished three monoterpene glycosides, 6-O-vanillyoxypaeoniflorin (1), muclanpioside-H (2), and galloyl-oxypaeoniflorin (3). Of the isolated compounds, compound 1 is a new compound. All isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (MIC) values in the range of 100 to 500 mu g/mL against eighteen pathogenic microorganisms of concern for public health or zoonosis.

引用

页码：815 / 820

页数：6

共 24 条

[1]

Screening of selected indigenous plants of Lebanon for antimicrobial activity [J].