Mechanism of action of the SPARI vilazodone: serotonin 1A partial agonist and reuptake inhibitor

被引：23

作者：

Stahl, Stephen M.

机构：

来源：

CNS SPECTRUMS | 2014年 / 19卷 / 02期

关键词：

MAJOR DEPRESSIVE DISORDER; DOUBLE-BLIND; RECEPTOR;

D O I：

10.1017/S1092852914000169

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

[No abstract available]

引用

收藏

页码：105 / 109

页数：5

相关论文

共 9 条

[1]

EMD 68843, a serotonin reuptake inhibitor with selective presynaptic 5-HT1A receptor agonistic properties [J].

Bartoszyk, GD ;

Hegenbart, R ;

Ziegler, H .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1997, 322 (2-3) :147-153

[2]

Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone [J].

Hughes, ZA ;

Staff, KR ;

Langmead, CJ ;

Hill, M ;

Bartoszyk, GD ;

Hagan, JJ ;

Middlemiss, DN ;

Dawson, LA .

EUROPEAN JOURNAL OF PHARMACOLOGY, 2005, 510 (1-2) :49-57

[3]

A Randomized, Double-Blind, Placebo-Controlled, 8-Week Study of Vilazodone, a Serotonergic Agent for the Treatment of Major Depressive Disorder [J].

Khan, Arif ;

Cutler, Andrew J. ;

Kajdasz, Daniel K. ;

Gallipoli, Susan ;

Athanasiou, Maria ;

Robinson, Donald S. ;

Whalen, Heidi ;

Reed, Carol R. .

JOURNAL OF CLINICAL PSYCHIATRY, 2011, 72 (04) :441-+

[4]

Behavioral and neurochemical effects of 5-{4-[4-(5-cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide (EMD 68843):: A combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine1A receptor partial agonist [J].

Page, ME ;

Cryan, JF ;

Sullivan, A ;

Dalvi, A ;

Saucy, B ;

Manning, DR ;

Lucki, I .

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 302 (03) :1220-1227

[5]

Drug action at the 5-HT1A receptor in vivo:: Autorecepror and postsynaptic receptor occupancy examined with PET and [carbonyl-11C]WAY-100635 [J].

Rabiner, EA ;

Gunn, RN ;

Wilkins, MR ;

Sargent, PA ;

Mocaer, E ;

Sedman, E ;

Cowen, PJ ;

Grasby, PM .

NUCLEAR MEDICINE AND BIOLOGY, 2000, 27 (05) :509-513

[6]

Evidence for Efficacy and Tolerability of Vilazodone in the Treatment of Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial [J].

Rickels, Karl ;

Athanasiou, Maria ;

Robinson, Donald S. ;

Gibertini, Michael ;

Whalen, Heidi ;

Reed, Carol R. .

JOURNAL OF CLINICAL PSYCHIATRY, 2009, 70 (03) :326-333

[7]

Vilazodone: a brief pharmacological and clinical review of the novel serotonin partial agonist and reuptake inhibitor [J].

Schwartz, Thomas L. ;

Siddiqui, Umar A. ;

Stahl, Stephen M. .

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY, 2011, 1 (03) :81-87

[8]

Stahl S., 2013, Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, V4th

[9]

Classifying psychotropic drugs by mode of action and not by target disorder [J].

Stahl, Stephen M. .

CNS SPECTRUMS, 2013, 18 (03) :113-117