1,6-bis(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)hexane

被引：5

作者：

Baell, JB

Gable, RW ^{[1
]}

Harvey, AJ

机构：

[1] Univ Melbourne, Sch Chem, Parkville, Vic 3010, Australia

[2] Walter & Eliza Hall Inst Med Res, Ctr Biotechnol, Struct Biol Chem Grp, Bundoora, Vic 3086, Australia

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2004年 / 60卷

关键词：

D O I：

10.1107/S1600536804011067

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The khellinone dimer, 1,6-bis-(5-acetyl-4,7-dimethoxybenzofuran-6-yloxy)hexane, C30H34O10, was prepared as part of a series of Kv1.3 ion channel blockers. The dimer lies on a centre of symmetry, and adopts an extended structure such that the separation between the benzofuran groups is 9.927 (3) Angstrom. C-H...O hydrogen bonds link the molecules into linear chains which lie parallel to the [201] direction.

引用

页码：O996 / O997

页数：2

共 5 条

[1] Khellinone derivatives as blockers of the voltage-gated potassium channel Kv1.3:: Synthesis and immunosuppressive activity [J].