Analysis of a cDNA sequence encoding a novel member of the snake venom metalloproteinase, disintegrin-like, cysteine-rich (MDC) protein family from Agkistrodon contortrix laticinctus

被引：22

作者：

deAraujo, HSS ^{[1
]}

deSouza, DHF ^{[1
]}

Ownby, CL ^{[1
]}

机构：

[1] OKLAHOMA STATE UNIV, DEPT ANAT PATHOL & PHARMACOL, STILLWATER, OK 74078 USA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY | 1997年 / 1342卷 / 02期

关键词：

metalloproteinase; disintegrin; snake venom; hemorrhagic toxin;

D O I：

10.1016/S0167-4838(97)00111-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this paper, we present a cDNA sequence encoding a full-length precursor form of a new member (ACLD) of the metalloproteinase-disintegrin-like protein family from the venom glands of Agkistrodon contortrix laticinctus (broad-banded copperhead) snake. Comparison of the deduced amino acid sequence of ACLD with those of other members of the metalloproteinase-disintegrin protein family from both mammalian and snake venom origin suggests that some conserved residues may be involved in processing of the disintegrin domain. (C) 1997 Elsevier Science B.V.

引用

页码：109 / 115

页数：7

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