RNA splicing: Unexpected spliceosome diversity

被引：28

作者：

Kreivi, JP

Lamond, AI

机构：

[1] Department of Biochemistry, University of Dundee, Dundee

来源：

CURRENT BIOLOGY | 1996年 / 6卷 / 07期

关键词：

D O I：

10.1016/S0960-9822(02)00599-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel form of spliceosome, containing the minor snRNPs U11 and U12, splices a class of pre-mRNA introns with non-consensus splice sites. This unexpected spliceosome diversity has interesting implications for the evolution acid expression of eukaryotic genes.

引用

收藏

页码：802 / 805

页数：4

相关论文

共 9 条

[1] SPLICED SEGMENTS AT 5' TERMINUS OF ADENOVIRUS 2 LATE MESSENGER-RNA [J].

BERGET, SM ;

MOORE, C ;

SHARP, PA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (08) :3171-3175

[2] AMAZING SEQUENCE ARRANGEMENT AT 5' ENDS OF ADENOVIRUS-2 MESSENGER-RNA [J].

CHOW, LT ;

GELINAS, RE ;

BROKER, TR ;

ROBERTS, RJ .

CELL, 1977, 12 (01) :1-8

[3] CONSERVED SEQUENCES IN A CLASS OF RARE EUKARYOTIC NUCLEAR INTRONS WITH NONCONSENSUS SPLICE SITES [J].

HALL, SL ;

PADGETT, RA .

JOURNAL OF MOLECULAR BIOLOGY, 1994, 239 (03) :357-365

[4] Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns [J].

Hall, SL ;

Padgett, RA .

SCIENCE, 1996, 271 (5256) :1716-1718

[5]

JACKSON IJ, 1991, NUCLEIC ACIDS RES, V19, P3795

[6] MULTIPLE ROLES FOR U6 SNRNA IN THE SPLICING PATHWAY [J].

MADHANI, HD ;

BORDONNE, R ;

GUTHRIE, C .

GENES & DEVELOPMENT, 1990, 4 (12B) :2264-2277

[7] ADDITIONAL LOW-ABUNDANCE HUMAN SMALL NUCLEAR RIBONUCLEOPROTEINS - U11, U12, ETC [J].

MONTZKA, KA ;

STEITZ, JA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (23) :8885-8889

[8]

MOORE MJ, 1993, RNA WORLD, P303

[9] A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro [J].

Tarn, WY ;

Steitz, JA .

CELL, 1996, 84 (05) :801-811