Do testosterone levels relate to aggression in elderly men with dementia?

被引：19

作者：

Orengo, C

Kunik, ME

Molinari, V

Wristers, K

Yudofsky, SC

机构：

[1] Baylor Coll Med, Dept Psychiat, Houston, TX 77030 USA

[2] Vet Affairs Med Ctr, Houston, TX 77030 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2002年 / 14卷 / 02期

关键词：

D O I：

10.1176/appi.neuropsych.14.2.161

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The aim of this study was to determine if testosterone and estrogen levels correlate with aggression in older men with dementia. Plasma total and free testosterone and estrogen levels and scores for behavioral disturbances, in particular aggression, were measured in 50 elderly males who had a diagnosis of dementia. Aggression was analyzed separately from agitation. Pearson correlations were calculated to determine the association between testosterone and estrogen and aggression. Linear regression analyses determined the influence of hormone levels on aggression, controlling for age, medical burden, and dementia severity. Free testosterone levels showed significant positive correlations with measures of aggression. Estrogen levels showed significant negative correlations with measures of aggression.

引用

页码：161 / 166

页数：6

共 32 条

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