Synthesis of alkylidenecyclopentenones via the coupling of propargyl alcohol derivatives with cyclopropylcarbene-chromium complexes

被引：17

作者：

Herndon, JW ^{[1
]}

Zhu, J

机构：

[1] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA

[2] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 01期

关键词：

D O I：

10.1021/ol990002s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The coupling of propargylic alcohols and their derivatives with cyclopropylcarbene-chromium complexes has been investigated. The coupling reaction leads to alkylidenecyclopentenones or alkoxyalkylcyclopentenones, depending on the leaving group ability of the propargyl substituent. A mechanism involving formation of a cyclpentadienone, followed by reduction and beta-elimination, was proposed.

引用

页码：15 / 18

页数：4

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