A facile tandem construction of C-O and C-C bonds: a novel one-pot transformation of Baylis-Hillman adducts into 2-benzoxepines

被引：40

作者：

Basavaiah, D ^{[1
]}

Sharada, DS ^{[1
]}

Veerendhar, A ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 15期

关键词：

Baylis-Hillman chemistry; 2-benzoxepines; para-formal-dehyde; Prins-type reaction; Friedel-Crafts reaction;

D O I：

10.1016/j.tetlet.2004.02.107

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile and one-pot synthesis of 2-benzoxepines, from Baylis-Hillman adducts that is, alkyl 3-aryl-3-hydroxy-2-methylenepropanoates, via treatment with HCHO in the presence of concd H2SO4, involving tandem construction of C-O and C-C bonds via Prins-type and Friedel-Crafts reactions, is described. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：3081 / 3083

页数：3

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