CT and MR Imaging Diagnosis and Staging of Hepatocellular Carcinoma: Part I. Development, Growth, and Spread: Key Pathologic and Imaging Aspects

被引:422
作者
Choi, Jin-Young [1 ]
Lee, Jeong-Min [2 ,3 ]
Sirlin, Claude B. [4 ]
机构
[1] Yonsei Univ Hlth Syst, Res Inst Radiol Sci, Dept Radiol, Seoul, South Korea
[2] Seoul Natl Univ Hosp, Dept Radiol, Seoul 110744, South Korea
[3] Seoul Natl Univ Hosp, Inst Radiat Med, Seoul 110744, South Korea
[4] Univ Calif San Diego, San Diego Med Ctr, Dept Radiol, Liver Imaging Grp, San Diego, CA 92103 USA
基金
美国国家卫生研究院;
关键词
PRIMARY LIVER CANCERS; GADOXETIC ACID; DYSPLASTIC NODULES; MAGNETIC-RESONANCE; CIRRHOTIC LIVER; ARTERIAL-PHASE; GADOBENATE DIMEGLUMINE; ENHANCED MRI; CLINICAL-SIGNIFICANCE; REGENERATIVE NODULES;
D O I
10.1148/radiol.14132361
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
100231 [临床病理学]; 100902 [航空航天医学];
摘要
Computed tomography (CT) and magnetic resonance (MR) imaging play critical roles in the diagnosis and staging of hepatocellular carcinoma (HCC). The first article of this two-part review discusses key concepts of HCC development, growth, and spread, emphasizing those features with imaging correlates and hence most relevant to radiologists; state-of-the-art CT and MR imaging technique with extracellular and hepatobiliary contrast agents; and the imaging appearance of precursor nodules that eventually may transform into overt HCC. (C) RSNA, 2014
引用
收藏
页码:634 / 653
页数:20
相关论文
共 147 条
[1]
CLONAL ANALYSIS OF REGENERATIVE NODULES IN HEPATITIS-C VIRUS-INDUCED LIVER-CIRRHOSIS [J].
AIHARA, T ;
NOGUCHI, S ;
SASAKI, Y ;
NAKANO, H ;
IMAOKA, S .
GASTROENTEROLOGY, 1994, 107 (06) :1805-1811
[2]
[Anonymous], 2010, WHO Classification of tumours of the Digestive System
[3]
Cellular and molecular mechanisms of hepatocellular carcinoma: an update [J].
Aravalli, Rajagopal N. ;
Cressman, Erik N. K. ;
Steer, Clifford J. .
ARCHIVES OF TOXICOLOGY, 2013, 87 (02) :227-247
[4]
Poorly versus moderately differentiated hepatocellular carcinoma: Vascularity assessment by computed tomographic hepatic angiography in correlation with histologically counted number of unpaired arteries [J].
Asayama, Yoshiki ;
Yoshimitsu, Kengo ;
Irie, Hiroyuki ;
Nishihara, Yunosuke ;
Aishima, Shinichi ;
Tajima, Tsuyoshi ;
Hirakawa, Masakazu ;
Ishigami, Kousei ;
Kakihara, Daisuke ;
Taketomi, Akinobu ;
Honda, Hiroshi .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2007, 31 (02) :188-192
[5]
Hepatocellular carcinoma in non-alcoholic fatty liver disease: An emerging menace [J].
Baffy, Gyoergy ;
Brunt, Elizabeth M. ;
Caldwell, Stephen H. .
JOURNAL OF HEPATOLOGY, 2012, 56 (06) :1384-1391
[6]
From the RSNA refresher courses - Screening the cirrhotic liver for hepatocellular carcinoma with CT and MR imaging: Opportunities and pitfalls [J].
Baron, RL ;
Peterson, MS .
RADIOGRAPHICS, 2001, 21 :S117-S132
[7]
Hepatocellular nodules in liver cirrhosis: contrast-enhanced MR [J].
Bartolozzi, Carlo ;
Battaglia, Valentina ;
Bozzi, Elena .
ABDOMINAL IMAGING, 2011, 36 (03) :290-299
[8]
BEASLEY RP, 1981, LANCET, V2, P1129
[9]
Brody Rachel I, 2012, Hepatology, V56, P382
[10]
Management of hepatoceullular carcinoma [J].
Bruix, J ;
Sherman, M .
HEPATOLOGY, 2005, 42 (05) :1208-1236