Antimalarial combinations

被引:217
作者
Kremsner, PG
Krishna, S
机构
[1] Univ Tubingen, Inst Trop Med, Dept Parasitol, D-72074 Tubingen, Germany
[2] Albert Schweitzer Hosp, Med Res Unit, Lambarene, Gabon
[3] Univ London St Georges Hosp, Sch Med, Dept Cellular & Mol Med, London SW17 0RE, England
关键词
D O I
10.1016/S0140-6736(04)16680-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Multidrug resistance has rendered monotherapy for malaria useless in most parts of the world, and has also compromised the usefulness of many of the available combination chemotherapies. New antimalarial regimens are, therefore, urgently needed. We review the various antimalarial combinations that can be used to treat otherwise drug-resistant disease, and discuss what defines an ideal antimalarial combination regimen.
引用
收藏
页码:285 / 294
页数:10
相关论文
共 113 条
[1]  
Adjuik M, 2004, LANCET, V363, P9, DOI 10.1016/S0140-6736(03)15162-8
[2]   Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children:: a randomised, multicentre trial [J].
Adjuik, M ;
Agnamey, P ;
Babiker, A ;
Borrmann, S ;
Brasseur, P ;
Cisse, M ;
Cobelens, F ;
Diallo, S ;
Faucher, JF ;
Garner, P ;
Gikunda, S ;
Kremsner, PG ;
Krishna, S ;
Lell, B ;
Loolpapit, M ;
Matsiegui, PB ;
Missinou, MA ;
Mwanza, J ;
Ntoumi, F ;
Olliaro, P ;
Osimbo, P ;
Rezbach, P ;
Some, E ;
Taylor, WRJ .
LANCET, 2002, 359 (9315) :1365-1372
[3]   Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial [J].
Alloueche, A ;
Bailey, W ;
Barton, S ;
Bwika, J ;
Chimpeni, P ;
Falade, CO ;
Fehintola, FA ;
Horton, J ;
Jaffar, S ;
Kanyok, T ;
Kremsner, PG ;
Kublin, JG ;
Lang, T ;
Missinou, MA ;
Mkandala, C ;
Oduola, AMJ ;
Premji, Z ;
Robertson, L ;
Sowunmi, A ;
Ward, SA ;
Winstanley, PA .
LANCET, 2004, 363 (9424) :1843-1848
[4]  
AMIES CR, 1930, B I MED RES FEDERATE, V2, P1
[5]   In vivo removal of malaria parasites from red blood cells without their destruction in acute falciparum malaria [J].
Angus, BJ ;
Chotivanich, K ;
Udomsangpetch, R ;
White, NJ .
BLOOD, 1997, 90 (05) :2037-2040
[6]  
Athan E, 2001, S AFR MED J, V91, P592
[7]   RESISTANCE TO CHLOROQUINE BY PLASMODIUM-VIVAX IN IRIAN-JAYA, INDONESIA [J].
BAIRD, JK ;
BASRI, H ;
PURNOMO ;
BANGS, MJ ;
SUBIANTO, B ;
PATCHEN, LC ;
HOFFMAN, SL .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1991, 44 (05) :547-552
[8]   An integrated assessment of the clinical safety of artemether-lumefantrine: a new oral fixed-dose combination antimalarial drug [J].
Bakshi, R ;
Hermeling-Fritz, I ;
Gathmann, I ;
Alteri, E .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2000, 94 (04) :419-424
[9]  
BASHAM D, 1998, NATURE, V393, P537
[10]   A trial of Fansidar® plus chloroquine or Fansidar® alone for the treatment of uncomplicated malaria in Gambian children [J].
Bojang, KA ;
Schneider, G ;
Forck, S ;
Obaro, SK ;
Jaffar, S ;
Pinder, M ;
Rowley, J ;
Greenwood, BM .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1998, 92 (01) :73-76