Replication fork arrest and DNA recombination

被引:208
作者
Michel, B [1 ]
机构
[1] INRA, Lab Genet Microbienne, F-78352 Jouy En Josas, France
关键词
D O I
10.1016/S0968-0004(00)01560-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Replication arrests are associated with genome rearrangements, which result from either homologous or non-homologous recombination. Interestingly, proteins involved in homologous recombination are able to convert an arrested replication fork into a recombination intermediate, which promotes replication restart and thus presumably prevents genome rearrangements.
引用
收藏
页码:173 / 178
页数:6
相关论文
共 35 条
[1]   Deletions at stalled replication forks occur by two different pathways [J].
Bierne, H ;
Ehrlich, SD ;
Michel, B .
EMBO JOURNAL, 1997, 16 (11) :3332-3340
[2]   THE REPLICATION TERMINATION SIGNAL TERB OF THE ESCHERICHIA-COLI CHROMOSOME IS A DELETION HOT-SPOT [J].
BIERNE, H ;
EHRLICH, SD ;
MICHEL, B .
EMBO JOURNAL, 1991, 10 (09) :2699-2705
[3]   Isolation of a dnaE mutation which enhances RecA-independent homologous recombination in the Escherichia coli chromosome [J].
Bierne, H ;
Vilette, D ;
Ehrlich, SD ;
Michel, B .
MOLECULAR MICROBIOLOGY, 1997, 24 (06) :1225-1234
[4]   WHEN REPLICATION FORKS STOP [J].
BIERNE, H ;
MICHEL, B .
MOLECULAR MICROBIOLOGY, 1994, 13 (01) :17-23
[5]   Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency [J].
Canceill, D ;
Viguera, E ;
Ehrlich, SD .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (39) :27481-27490
[6]   Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli [J].
Canceill, D ;
Ehrlich, SD .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (13) :6647-6652
[7]   COPY-CHOICE ILLEGITIMATE DNA RECOMBINATION REVISITED [J].
DALENCON, E ;
PETRANOVIC, M ;
MICHEL, B ;
NOIROT, P ;
AUCOUTURIER, A ;
UZEST, M ;
EHRLICH, SD .
EMBO JOURNAL, 1994, 13 (11) :2725-2734
[8]   Evolution of simple repeats in DNA and their relation to human disease [J].
Djian, P .
CELL, 1998, 94 (02) :155-160
[9]  
HILL TM, 1996, ESCHERICHIA COLI SAL, P1602
[10]   RECOMBINATIONAL RESCUE OF THE STALLED DNA-REPLICATION FORK - A MODEL-BASED ON ANALYSIS OF AN ESCHERICHIA-COLI STRAIN WITH A CHROMOSOME REGION DIFFICULT TO REPLICATE [J].
HORIUCHI, T ;
FUJIMURA, Y .
JOURNAL OF BACTERIOLOGY, 1995, 177 (03) :783-791