Pulmonary alveolar proteinosis: a complication in patients with hematologic malignancy

被引：8

作者：

Birsak, CA

van Rossem, RN

Nijhuis-Heddes, JMA

Maartense, E

机构：

[1] Reinier de Graaf Gasthuis, Dept Internal Med, NL-2625 AD Delft, Netherlands

[2] Reinier de Graaf Gasthuis, Dept Pulmonol, NL-2625 AD Delft, Netherlands

来源：

NETHERLANDS JOURNAL OF MEDICINE | 2000年 / 56卷 / 05期

关键词：

pulmonary alveolar proteinosis; acute myeloid leukemia; PAS staining;

D O I：

10.1016/S0300-2977(00)00025-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present the case of a patient with acute myeloid leukemia and secondary Pulmonary Alveolar Proteinosis (PAP), which is an underestimated cause of a persistent pulmonary infiltrate in patients with hematologic malignancies often accompanied by neutropenia due to therapy. Diagnosis is established by performing Periodic Acid-Schiff reaction (PAS) stains and transmission electron microscopy (EM) on bronchoalveolar lavage (BAL) fluid. We wish to stress the importance of the early recognition of PAP, which is potentially reversible, and routinely performing PAS staining on BAL fluid in patients with a hematologic disease especially myeloid disorders and a persistent lung infiltrate. (C) 2000 Published by Elsevier Science BN. All rights reserved.

引用

页码：193 / 197

页数：5

共 30 条

[1]

Asamoto H, 1995, Nihon Kyobu Shikkan Gakkai Zasshi, V33, P835

[2]

BEDROSSIAN CWM, 1980, HUM PATHOL, V11, P527

[3] GRANULAR PNEUMOCYTES - ELECTRON MICROSCOPIC EVIDENCE OF THEIR EXOCRINIC FUNCTION [J].