Chemistry of the genus Allium .2. The flavonoids of Allium neapolitanum

被引:48
作者
Carotenuto, A
Fattorusso, E
Lanzotti, V
Magno, S
DeFeo, V
Cicala, C
机构
[1] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM SOSTANZE NAT,I-80131 NAPLES,ITALY
[2] UNIV MOLISE,DIPARTIMENTO SCI & TECNOL AGROALIMENTARI AMBIENTA,I-86100 CAMPOBASSO,ITALY
[3] UNIV SALERNO,FAC FARM,I-84084 PENTA,SALERNO,ITALY
[4] UNIV NAPLES FEDERICO II,DIPARTIMENTO FARMACOL SPERIMENTALE,I-80131 NAPLES,ITALY
关键词
Allium neapolitanum; Liliaceae; flavonol glycosides; branched trisaccharides; anti-platelet aggregation activity;
D O I
10.1016/S0031-9422(96)00663-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An investigation of the extracts from Allium neapolitanum has led to the isolation of 13 flavonoid glycosides, based on kaempferol, quercetin and isorhamnetin. Four of them are new compounds and have been identified as: kaempferol 3-O-{[2-O-alpha-L-rhamnopyranosyl-4-O-beta-D-glucopyranosyl]-beta-D-glucopyranoside}, isorhamnetin 3-O-{[2-O-alpha-L-rhamnopyranosyl-6-O-beta-D-glucopyranosyl]-beta-D-glucopyranoside}, isorhamnetin 3-O-{[2-O-alpha-L-rhamnopyranosyl-6-O-beta-D-glucopyranosyl]-beta-D-glucopyranoside}-7- O-beta-D-glucopyranoside and isorhamnetin 3-O-{[2-O-alpha-L-rhamnopyranosyl-6-O-beta-D-gentiobiosyl]-beta-D-glucopyranoside}. The isolated compounds were evaluated for their anti-aggregation human platelet activity. Copyright (C) 1997 Elsevier Science Ltd.
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页码:949 / 957
页数:9
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