PrP genetics in sheep and the implications for scrapie and BSE

被引：195

作者：

Hunter, N

机构：

[1] Institute for Animal Health, BBSRC/MRC Neuropathogenesis Unit, Edinburgh, EH9 3JF, West Mains Road

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 08期

关键词：

D O I：

10.1016/S0966-842X(97)01081-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The strong links between PrP genotype and the occurrence of scrapie in sheep strengthen evidence supporting the central importance of the PrP protein in the development of transmissible spongiform encephalopathies, despite the fact that the cattle PrP gene has, so far, failed to show any association between PrP alleles and susceptibility to BSE.

引用

页码：331 / 334

页数：4

共 36 条

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