Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer

被引：22

作者：

Shen, Zhihong ^{[1
]}

Liu, Xibo ^{[1
]}

Lu, Baochun ^{[1
]}

Ye, Minfeng ^{[1
]}

机构：

[1] Zhejiang Univ, Shaoxing Hosp, Shaoxing Peoples Hosp, Dept Gen Surg, 568 Zhongxing North Rd, Shaoxing 312000, Zhejiang, Peoples R China

来源：

ONCOLOGY LETTERS | 2016年 / 11卷 / 02期

关键词：

hepatoid adenocarcinoma of stomach; gastric cancer; alpha-fetoprotein; chemotherapy; prognosis; ALPHA-FETOPROTEIN; FEATURES; SUBTYPE;

D O I：

10.3892/ol.2015.4023

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Hepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric cancer with an extremely poor prognosis. The current study reports a rare case of HAS, characterized by gastric cancer and infiltration of cancer cells into the left liver lobe, as well as lymphadenectasis. The expression of a-fetoprotein (AFP) was markedly increased in the tumor cells of the liver neoplasms. A gastric biopsy indicated highly, moderately and poorly differentiated papillary adenocarcinoma. The patient underwent two cycles of chemotherapy with oxaliplatin (130 mg; day 1) and capecitabine (2 mg, twice daily; days 1-14). At 7 weeks after the chemotherapy, an expanded gastrectomy and radical resection of left lung lobe were performed on the operable lesion. AFP expression was significantly decreased following the procedure. A literature review was also conducted by searching PubMed/Medline, indicating that surgery and chemotherapy may positively affect the outcomes of HAS patients.

引用

页码：1077 / 1080

页数：4

共 14 条

[1]

Hepatoid adenocarcinoma of the stomach: an unusual case of elevated alpha-fetoprotein with prior treatment for hepatocellular carcinoma [J].