Epidemiology and Natural History of Non-Alcoholic Steatohepatitis

被引:386
作者
Argo, Curtis K. [1 ]
Caldwell, Stephen H. [1 ]
机构
[1] Univ Virginia Hlth Syst, Div Gastroenterol & Hepatol, Charlottesville, VA 22908 USA
关键词
Fatty liver; Steatohepatitis; Outcomes; Epidemiology; Obesity; FATTY LIVER-DISEASE; SERUM ALANINE AMINOTRANSFERASE; LONG-TERM OUTCOMES; INSULIN-RESISTANCE; CRYPTOGENIC CIRRHOSIS; METABOLIC SYNDROME; HEPATIC STEATOSIS; RISK-FACTORS; FOLLOW-UP; HEPATOCELLULAR-CARCINOMA;
D O I
10.1016/j.cld.2009.07.005
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition in many parts of the world. This article describes the epidemiology and natural history of this disorder. It also describes current diagnostic and treatment methods and describes future implications NAFLD may have.
引用
收藏
页码:511 / +
页数:22
相关论文
共 158 条
[1]
Familial aggregation of insulin resistance in first-degree relatives of patients with nonalcoholic fatty liver disease [J].
Abdelmalek, Manal F. ;
Liu, Chen ;
Shuster, Jonathan ;
Nelson, David R. ;
Asal, Nabih R. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (09) :1162-1169
[2]
The natural history of nonalcoholic fatty liver disease: A population-based cohort study [J].
Adams, LA ;
Lymp, JF ;
St Sauver, J ;
Sanderson, SO ;
Lindor, KD ;
Feldstein, A ;
Angulo, P .
GASTROENTEROLOGY, 2005, 129 (01) :113-121
[3]
The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies [J].
Adams, LA ;
Sanderson, S ;
Lindor, KD ;
Angulo, P .
JOURNAL OF HEPATOLOGY, 2005, 42 (01) :132-138
[4]
CD36, insulin resistance, and coronary heart disease [J].
Aitman, TJ .
LANCET, 2001, 357 (9257) :651-652
[5]
Intermittent disconjugate gaze: A novel finding in nonalcoholic steatohepatitis and cryptogenic cirrhosis [J].
Al-Osaimi, AMS ;
Berg, CL ;
Caldwell, SH .
HEPATOLOGY, 2005, 41 (04) :943-943
[6]
ALOSAIMI, 1995, HEPATOLOGY, V42, P1095
[7]
Fatty liver: Experience from western India [J].
Amarapurkar, Anjali ;
Ghansar, Tanveer .
ANNALS OF HEPATOLOGY, 2007, 6 (01) :37-40
[8]
Nonalcoholic fatty liver disease and liver transplantation [J].
Angulo, P .
LIVER TRANSPLANTATION, 2006, 12 (04) :523-534
[9]
Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis [J].
Angulo, P ;
Keach, JC ;
Batts, KP ;
Lindor, KD .
HEPATOLOGY, 1999, 30 (06) :1356-1362
[10]
Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis [J].
Argo, Curtis K. ;
Northup, Patrick G. ;
Al-Osaimi, Abdullah M. S. ;
Caldwell, Stephen H. .
JOURNAL OF HEPATOLOGY, 2009, 51 (02) :371-379