Tetracycline Susceptibility Testing and Resistance Genes in Isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus Complex from a US Military Hospital

被引：45

作者：

Akers, Kevin S.

Mende, Katrin ^{[3
]}

Yun, Heather C. ^{[2
]}

Hospenthal, Duane R. ^{[2
]}

Beckius, Miriam L.

Yu, Xin

Murray, Clinton K. ^{[1
,2
]}

机构：

[1] Brooke Army Med Ctr, Infect Dis Serv, San Antonio Mil Med Ctr, Ft Sam Houston, TX 78234 USA

[2] Uniformed Serv Univ Hlth Sci, Bethesda, MD 20814 USA

[3] Infect Dis Clin Res Program, San Antonio, TX USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 06期

关键词：

IDENTIFICATION; SPP;

D O I：

10.1128/AAC.01405-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Infections with multidrug-resistant Acinetobacter baumannii-Acinetobacter calcoaceticus complex bacteria complicate the care of U. S. military personnel and civilians worldwide. One hundred thirty-three isolates from 89 patients at our facility during 2006 and 2007 were tested by disk diffusion, Etest, and broth microdilution for susceptibility to tetracycline, doxycycline, minocycline, and tigecycline. Minocycline was the most active in vitro, with 90% of the isolates tested susceptible. Susceptibilities varied significantly with the testing method. The acquired tetracycline resistance genes tetA, tetB, and tetA( 39) were present in the isolates.

引用

页码：2693 / 2695

页数：3

共 13 条

[1] The tetracycline resistance determinant Tet 39 and the sulphonamide resistance gene sulII are common among resistant Acinetobacter spp. isolated from integrated fish farms in Thailand [J].