Super quenching behavior between a conjugated polymer and molecular quenchers and its application in biological/chemical sensors

被引：3

作者：

Chen, LH ^{[1
]}

McBranch, D ^{[1
]}

Whitten, D ^{[1
]}

机构：

[1] Los Alamos Natl Lab, Ctr Mat Sci, Los Alamos, NM 87545 USA

来源：

ADVANCED MATERIALS AND OPTICAL SYSTEMS FOR CHEMICAL AND BIOLOGICAL DETECTION | 1999年 / 3858卷

关键词：

fluorescence quenching; conjugated polymer; biological sensor; chemical sensor;

D O I：

10.1117/12.372927

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The fluorescence of an ionic conjugated polymer can be efficiently quenched by the small molecular quenchers wherein one quencher molecule may quench the fluorescence of virtually an entire polymer chain. This leads to "static" Stern-Volmer quenching constants as high as 10(7) - 10(9) M-1. A new class of highly sensitive chemical and biological sensors has been developed based on this unique quenching phenomenon.

引用

页码：32 / 39

页数：8

共 28 条

[1] CONJUGATED POLYMER-FILMS FOR GAS SEPARATIONS
ANDERSON, MR
MATTES, BR
REISS, H
KANER, RB
[J]. SCIENCE, 1991, 252 (5011) : 1412 - 1415
[2] LIGHT-EMITTING-DIODES BASED ON CONJUGATED POLYMERS
BURROUGHES, JH
BRADLEY, DDC
BROWN, AR
MARKS, RN
MACKAY, K
FRIEND, RH
BURN, PL
HOLMES, AB
[J]. NATURE, 1990, 347 (6293) : 539 - 541
[3] GANGLIOSIDES AND MEMBRANE RECEPTORS FOR CHOLERA TOXIN
CUATRECASAS, P
[J]. BIOCHEMISTRY, 1973, 12 (18) : 3558 - 3566
[4] INTERACTION OF VIBRIO-CHOLERAE ENTEROTOXIN WITH CELL-MEMBRANES
CUATRECASAS, P
[J]. BIOCHEMISTRY, 1973, 12 (18) : 3547 - 3558
[5] Emerging fluorescence sensing technologies: From photophysical principles to cellular applications
de Silva, AP
Eilers, J
Zlokarnik, G
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (15) : 8336 - 8337
[6] Fuzzy nanoassemblies: Toward layered polymeric multicomposites
Decher, G
[J]. SCIENCE, 1997, 277 (5330) : 1232 - 1237
[7] Photoinduced electron transfer in dendritic macromolecules. 1. Intermolecular electron transfer
Devadoss, C
Bharathi, P
Moore, JS
[J]. MACROMOLECULES, 1998, 31 (23) : 8091 - 8099
[8] INTERACTION OF CHOLERAGEN WITH OLIGOSACCHARIDE OF GANGLIOSIDE GM1 - EVIDENCE FOR MULTIPLE OLIGOSACCHARIDE BINDING-SITES
FISHMAN, PH
MOSS, J
OSBORNE, JC
[J]. BIOCHEMISTRY, 1978, 17 (04) : 711 - 716
[9] Interfacial properties of biotin conjugate-avidin complexes studied by acoustic wave sensor
Ghafouri, S
Thompson, M
[J]. LANGMUIR, 1999, 15 (02) : 564 - 572
[10] Green N M, 1975, Adv Protein Chem, V29, P85, DOI 10.1016/S0065-3233(08)60411-8

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