Asian genotypes of JC virus in Japanese-Americans suggest familial transmission

被引:32
作者
Suzuki, M
Zheng, HY
Takasaka, T
Sugimoto, C
Kitamura, T
Beutler, E
Yogo, Y
机构
[1] Univ Tokyo, Dept Urol, Fac Med, Bunkyo Ku, Tokyo 1138655, Japan
[2] Scripps Res Inst, Dept Mol & Expt Med, La Jolla, CA 92037 USA
[3] Univ Tokyo, Inst Med Sci, Dept Microbiol & Immunol, Lab Viral Infect,Minato Ku, Tokyo 1088639, Japan
关键词
D O I
10.1128/JVI.76.19.10074-10078.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
To examine the mode of JC virus (JCV) transmission, we collected urine samples from second- and third-generation Japanese-Americans in Los Angeles, Calif., whose parents and grandparents were all Japanese. From the urine samples of these Japanese-Americans, we mainly detected two subtypes (CY and MY) of JCV that are predominantly found among native Japanese. This finding provides support for the hypothesis that JCV is transmitted mainly within the family through long-term cohabitation.
引用
收藏
页码:10074 / 10078
页数:5
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