Manipulation of free carbohydrates via stannylene acetals. Preparation of beta-per-O-acyl derivatives of D-mannose, L-rhamnose, 6-O-trityl-D-talose, and D-lyxose

被引：16

作者：

Hodosi, G ^{[1
]}

Kovac, P ^{[1
]}

机构：

[1] NIDDK,NIH,BETHESDA,MD 20892

来源：

CARBOHYDRATE RESEARCH | 1997年 / 303卷 / 02期

关键词：

stannylene complexes; 1,2-O-cis-stannylene acetals; beta-mannose; beta-rhamnose; beta-talose; beta-lyxose;

D O I：

10.1016/S0008-6215(97)00155-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple and high-yielding method for the preparation of 1-O-beta-acyl derivatives of carbohydrates with an axial OH group at C-2 is described. It utilizes the property of unprotected carbohydrates to preferentially form 1,2-O-cis stannylene acetals, when treated with dibutyltin oxide. These acetals can be acylated with retention of configuration at the anomeric position. (C) 1997 Elsevier Science Ltd.

引用

页码：239 / 243

页数：5

共 21 条

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[2]

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[4]

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