The Upregulation of Immune Checkpoint Ligand PD-L1 in Tumour Microenvironment

被引:7
作者
Xu, W. [1 ]
Jiang, H. [1 ]
Gao, J. [1 ]
Zhao, Y. [1 ]
机构
[1] Beijing Mil Gen Hosp, Dept Radiat Oncol, Beijing 100700, Peoples R China
关键词
DRIVEN;
D O I
10.1111/sji.12177
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:71 / 72
页数:2
相关论文
共 6 条
[1]   Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors [J].
Akbay, Esra A. ;
Koyama, Shohei ;
Carretero, Julian ;
Altabef, Abigail ;
Tchaicha, Jeremy H. ;
Christensen, Camilla L. ;
Mikse, Oliver R. ;
Cherniack, Andrew D. ;
Beauchamp, Ellen M. ;
Pugh, Trevor J. ;
Wilkerson, Matthew D. ;
Fecci, Peter E. ;
Butaney, Mohit ;
Reibel, Jacob B. ;
Soucheray, Margaret ;
Cohoon, Travis J. ;
Janne, Pasi A. ;
Meyerson, Matthew ;
Hayes, D. Neil ;
Shapiro, Geoffrey I. ;
Shimamura, Takeshi ;
Sholl, Lynette M. ;
Rodig, Scott J. ;
Freeman, Gordon J. ;
Hammerman, Peter S. ;
Dranoff, Glenn ;
Wong, Kwok-Kin .
CANCER DISCOVERY, 2013, 3 (12) :1355-1363
[2]   Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice [J].
Deng, Liufu ;
Liang, Hua ;
Burnette, Byron ;
Beckett, Michael ;
Darga, Thomas ;
Weichselbaum, Ralph R. ;
Fu, Yang-Xin .
JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (02) :687-695
[3]   The blockade of immune checkpoints in cancer immunotherapy [J].
Pardoll, Drew M. .
NATURE REVIEWS CANCER, 2012, 12 (04) :252-264
[4]   Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma [J].
Parsa, Andrew T. ;
Waldron, James S. ;
Panner, Amith ;
Crane, Courtney A. ;
Parney, Ian F. ;
Barry, Jeffrey J. ;
Cachola, Kristine E. ;
Murray, Joseph C. ;
Tihan, Tarik ;
Jensen, Michael C. ;
Mischel, Paul S. ;
Stokoe, David ;
Pieper, Russell O. .
NATURE MEDICINE, 2007, 13 (01) :84-88
[5]   Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells [J].
Spranger, Stefani ;
Spaapen, Robbert M. ;
Zha, Yuanyuan ;
Williams, Jason ;
Meng, Yuru ;
Ha, Thanh T. ;
Gajewski, Thomas F. .
SCIENCE TRANSLATIONAL MEDICINE, 2013, 5 (200)
[6]   Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape [J].
Taube, Janis M. ;
Anders, Robert A. ;
Young, Geoffrey D. ;
Xu, Haiying ;
Sharma, Rajni ;
McMiller, Tracee L. ;
Chen, Shuming ;
Klein, Alison P. ;
Pardoll, Drew M. ;
Topalian, Suzanne L. ;
Chen, Lieping .
SCIENCE TRANSLATIONAL MEDICINE, 2012, 4 (127)