Studies on antitussive activity of Drymaria cordata Willd (Caryophyllaceae)

被引：20

作者：

Mukherjee, PK ^{[1
]}

Saha, K ^{[1
]}

Bhattacharya, S ^{[1
]}

Giri, SN ^{[1
]}

Pal, M ^{[1
]}

Saha, BP ^{[1
]}

机构：

[1] JADAVPUR UNIV,FAC ENGN & TECHNOL,DEPT PHARMACEUT TECHNOL,CALCUTTA 700032,W BENGAL,INDIA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1997年 / 56卷 / 01期

关键词：

Drymaria cordata; antitussive; sulfur dioxide; cough; methanol extract;

D O I：

10.1016/S0378-8741(97)01512-2

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The methanol extract of Drymaria cordata Willd. was investigated for its effect on a cough model induced by sulfur dioxide gas in mice. It exhibited significant antitussive activity when compared with the control in a dose-dependent manner. The antitussive activity of the extract was comparable to that of codeine phosphate, a prototype antitussive agent. The D. cordata extract (100, 200, 400 mg/kg) showed 11.6%, 31.6% and 51.5% inhibition of cough with respect to the control group. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：77 / 80

页数：4

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