The effects of low-intensity pulsed ultrasound on bioabsorbable self-reinforced poly L-lactide screws

被引:15
作者
Handolin, L
Pohjonen, T
Partio, EK
Arnala, I
Törmälä, P
Rokkanen, P
机构
[1] Univ Helsinki, Cent Hosp, Dept Orthopaed & Traumatol, FIN-00260 Helsinki, Finland
[2] Tampere Univ Technol, Inst Biomat, Tampere, Finland
[3] Dextra Med Ctr, FIN-00350 Helsinki, Finland
[4] Kanta Hame Cent Hosp, FIN-13530 Hameenlinna, Finland
基金
芬兰科学院;
关键词
bioabsorbable SR-PLLA implant; low-intensity ultrasound; mechanical properties; molecular properties;
D O I
10.1016/S0142-9612(02)00006-6
中图分类号
R318 [生物医学工程];
学科分类号
0831 [生物医学工程];
摘要
The effects of low-intensity pulsed ultrasound on the mechanical and molecular properties of self-reinforced Poly L-lactide (SR-PLLA) screws were studied in vitro. SR-PLLA screws of 4.5mm diameter ere exposed on low-intensity ultrasound for 1, 3, 6, 9 and 12 weeks. After exposure, the bending strength, shear strength, and molecular weight were investigated. There were no differences in the ienvstigated properties between the ultrasound exposure and control groups. We found no evidence that low-intensity ultrasound has any effect on the mechanical or molecular properties of SR-PLLA screws in vitro. The present results suggest that biodegradable SR-PLLA fixation devices are compatible with low-intensity ultrasound in vitro. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2733 / 2736
页数:4
相关论文
共 15 条
[1]
AGRANOVICH MS, 1994, FUNKTSIONAL ANAL PRI, V28, P1
[2]
[Anonymous], J ORTHOP TRAUMA
[3]
Gebauer D, 2000, J ORTHOP TRAUMA, V14, P154
[4]
GILDING DK, 1981, BIOCOMPATIBILITY CLI, V2, P209
[5]
HEEMA JD, 1994, J BONE JT SURG A, V76, P26
[6]
ABSORBABLE POLYGLYCOLIDE PINS IN FIXATION OF DISPLACED FRACTURES OF THE RADIAL HEAD [J].
HIRVENSALO, E ;
BOSTMAN, O ;
ROKKANEN, P .
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 1990, 109 (05) :258-261
[7]
HOLLINGER JO, 1986, CLIN ORTHOP RELAT R, P290
[8]
A bioabsorbable self-expandable, self-reinforced poly-L-lactic acid urethral stent for recurrent urethral strictures:: A preliminary report [J].
Isotalo, T ;
Tammela, TLJ ;
Talja, M ;
Välimaa, T ;
Törmälä, P .
JOURNAL OF UROLOGY, 1998, 160 (06) :2033-2036
[9]
Fixation of mandibular body osteotomies using biodegradable amorphous self-reinforced (70L:30DL) polylactide or metal lag screws:: an experimental study in sheep [J].
Kallela, I ;
Tulamo, RM ;
Hietanen, J ;
Pohjonen, T ;
Suuronen, R ;
Lindqvist, C .
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 1999, 27 (02) :124-133
[10]
ULTRASOUND-ENHANCED POLYMER DEGRADATION AND RELEASE OF INCORPORATED SUBSTANCES - (CONTROLLED RELEASE DRUG DELIVERY SYSTEMS) [J].
KOST, J ;
LEONG, K ;
LANGER, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (20) :7663-7666