The influence of glycerol on the transport of light in the skin

被引:27
作者
Bashkatov, AN [1 ]
Genina, EA [1 ]
Sinichkin, YP [1 ]
Tuchin, VV [1 ]
机构
[1] Saratov NG Chernyshevskii State Univ, Dept Opt, Saratov, Russia
来源
FUNCTIONAL MONITORING AND DRUG-TISSUE INTERACTION | 2002年 / 4623卷
关键词
light scattering; skin; osmolytes; refractive index matching;
D O I
10.1117/12.469442
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
We present experimental results on optical properties of the rat skin controlled by administration of osmotic chemical, such as glycerol. Administration of glycerol induces matter diffusion and as a result equalization of the refractive indices of skin scatterers and interstitial fluid. The significant increase of the skin sample transmittance under action of glycerol has been demonstrated. The mean value of the glycerol diffusion coefficient has been estimated as 5.1 - 10(-7) +/- 2.3 - 10(-7) cm(2)/sec.
引用
收藏
页码:144 / 152
页数:9
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