Longitudinal evaluation of leukoaraiosis with whole brain ADC histograms

被引：21

作者：

Mascalchi, M

Moretti, M

Della Nave, R

Lolli, F

Tessa, C

Carlucci, G

Bartolini, L

Pracucci, G

Pantoni, L

Filippi, M

Inzitari, D

机构：

[1] Univ Florence, Dipartimento Fisiopatol Clin, Radiodiagnost Sect, Florence, Italy

[2] Univ Florence, Dept Neurol Sci, Florence, Italy

[3] Ist Sci San Raffaele, Dept Neurosci, Neuroimaging Res Unit, Milan, Italy

[4] Univ Osped San Raffaele, Milan, Italy

来源：

NEUROLOGY | 2002年 / 59卷 / 06期

关键词：

D O I：

10.1212/WNL.59.6.938

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

FLAIR and diffusion-weighted MRI were obtained twice (mean interval 20 +/- 4 months) in 10 patients with leukoaraiosis. At follow-up, visual extension of leukoaraiosis was unchanged, whereas the median of whole brain apparent diffusion coefficient (WB-ADC) histogram was increased (p = 0.008) and brain volume index (BVI) was decreased (p = 0.006). WB-ADC histogram and BVI are sensitive to leukoaraiosis and might be considered for monitoring progression of the disease.

引用

页码：938 / 940

页数：3

共 10 条

[1] Clinical severity in CADASIL related to ultrastructural damage in white matter - In vivo study with diffusion tensor MRI [J].