Oxidized phosphatidylcholines: Pattern recognition ligands for multiple pathways of the innate immune response

被引:30
作者
Hazen, SL
Chisolm, GM
机构
[1] Cleveland Clin Fdn, Dept Cell Biol, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Dept Cardiovasc Med, Cleveland, OH 44195 USA
关键词
D O I
10.1073/pnas.212532799
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:12515 / 12517
页数:3
相关论文
共 36 条
[1]   Complement and atherogenesis - Binding of CRP to degraded, nonoxidized LDL enhances complement activation [J].
Bhakdi, S ;
Torzewski, M ;
Klouche, M ;
Hemmes, M .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1999, 19 (10) :2348-2354
[2]   Novel clinical markers of vascular wall inflammation [J].
Blake, GJ ;
Ridker, PM .
CIRCULATION RESEARCH, 2001, 89 (09) :763-771
[3]   The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein [J].
Boullier, A ;
Gillotte, KL ;
Hörkkö, S ;
Green, SR ;
Friedmann, P ;
Dennis, EA ;
Witztum, JL ;
Steinberg, D ;
Quehenberger, O .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (13) :9163-9169
[4]   C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids [J].
Chang, MK ;
Binder, CJ ;
Torzewski, M ;
Witztum, JL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (20) :13043-13048
[5]   Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages:: Evidence that oxidation-specific epitopes mediate macrophage recognition [J].
Chang, MK ;
Bergmark, C ;
Laurila, A ;
Hörkkö, S ;
Han, KH ;
Friedman, P ;
Dennis, EA ;
Witztum, JL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (11) :6353-6358
[6]   The oxidative modification hypothesis of atherogenesis: An overview [J].
Chisolm, GM ;
Steinberg, D .
FREE RADICAL BIOLOGY AND MEDICINE, 2000, 28 (12) :1815-1826
[7]   LOW-DENSITY LIPOPROTEIN AND VERY LOW-DENSITY LIPOPROTEIN ARE SELECTIVELY BOUND BY AGGREGATED C-REACTIVE PROTEIN [J].
DEBEER, FC ;
SOUTAR, AK ;
BALTZ, ML ;
TRAYNER, IM ;
FEINSTEIN, A ;
PEPYS, MB .
JOURNAL OF EXPERIMENTAL MEDICINE, 1982, 156 (01) :230-242
[8]   Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice [J].
Febbraio, M ;
Podrez, EA ;
Smith, JD ;
Hajjar, DP ;
Hazen, SL ;
Hoff, HF ;
Sharma, K ;
Silverstein, RL .
JOURNAL OF CLINICAL INVESTIGATION, 2000, 105 (08) :1049-1056
[9]   Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids -: Importance of Schiff base formation and aldol condensation [J].
Friedman, P ;
Hörkkö, S ;
Steinberg, D ;
Witztum, JL ;
Dennis, EA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (09) :7010-7020
[10]   Macrophage uptake of low-density lipoprotein bound to aggregated C-reactive protein: possible mechanism of foam-cell formation in atherosclerotic lesions [J].
Fu, T ;
Borensztajn, J .
BIOCHEMICAL JOURNAL, 2002, 366 (01) :195-201