DsbA: a protein-folding catalyst contributing to bacterial virulence

被引:60
作者
Yu, J [1 ]
Kroll, JS [1 ]
机构
[1] St Marys Hosp, Imperial Coll Sch Med, Dept Paediat, Mol Infect Dis Grp, London W2 1PG, England
基金
英国惠康基金;
关键词
DsbA; protein-folding; pathogenicity;
D O I
10.1016/S1286-4579(99)00239-7
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
DsbA, a periplasmic thiol:disulphide oxidoreductase, catalyses the folding of various factors, among which are virulence determinants or the components of type III secretory machinery. It is also necessary for intracellular survival and cell-to-cell spread of the intracellular pathogen Shigella flexneri. (C) 1999 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:1221 / 1228
页数:8
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