Treatment of scleromyxedema with 2-chlorodeoxyadenosine

被引：23

作者：

Davis, LS ^{[1
]}

Sanal, S ^{[1
]}

Sangueza, OP ^{[1
]}

机构：

[1] MED COLL GEORGIA,DEPT PATHOL,AUGUSTA,GA 30912

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1996年 / 35卷 / 02期

关键词：

D O I：

10.1016/S0190-9622(96)90650-7

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Scleromyxedema is an unusual skin disease that is characterized by a proliferation of fibroblasts and an accumulation of mucin. Despite experience with multiple forms of therapy, no single agent has proved uniformly beneficial in this condition. We describe a patient with scleromyxedema who was treated successfully with 2-chlorodeoxyadenosine (2-CdA), a purine analog used mainly in the treatment of lymphoproliferative disorders.

引用

页码：288 / 290

页数：3

共 12 条

[1] POTENT TOXICITY OF 2-CHLORODEOXYADENOSINE TOWARD HUMAN MONOCYTES INVITRO AND INVIVO - A NOVEL-APPROACH TO IMMUNOSUPPRESSIVE THERAPY
CARRERA, CJ
TERAI, C
LOTZ, M
CURD, JG
PIRO, LD
BEUTLER, E
CARSON, DA
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1990, 86 (05) : 1480 - 1488
[2] LICHEN MYXEDEMATOSUS SERUM STIMULATES HUMAN-SKIN FIBROBLAST PROLIFERATION
HARPER, RA
RISPLER, J
[J]. SCIENCE, 1978, 199 (4328) : 545 - 547
[3] TREATMENT OF SCLEROMYXEDEMA WITH MELPHALAN
HARRIS, RB
PERRY, HO
KYLE, RA
WINKELMANN, RK
[J]. ARCHIVES OF DERMATOLOGY, 1979, 115 (03) : 295 - 299
[4] LICHEN MYXEDEMATOSUS - DERMAL INFILTRATIVE DISORDER RESPONSIVE TO CYCLOPHOSPHAMIDE THERAPY
HOWSDEN, SM
HERNDON, JH
FREEMAN, RG
[J]. ARCHIVES OF DERMATOLOGY, 1975, 111 (10) : 1325 - 1330
[5] SUCCESSFUL TREATMENT OF SCLEROMYXEDEMA WITH PLASMAPHERESIS AND IMMUNOSUPPRESSION
KEONG, CH
ASAKA, Y
FUKURO, S
MIYAMOTO, C
KATSUMATA, M
IINO, Y
KOMIYA, T
[J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1990, 22 (05) : 842 - 844
[6] LEVER WF, 1990, HISTOPATHOLOGY SKIN, P472
[7] SCLEROMYXEDEMA - SUCCESSFUL TREATMENT WITH PLASMA-EXCHANGE AND IMMUNOSUPPRESSION
MACFARLANE, AW
DAVENPORT, A
VERBOV, JL
GOLDSMITH, HJ
[J]. BRITISH JOURNAL OF DERMATOLOGY, 1987, 117 (05) : 653 - 657
[8] 2-CHLORODEOXYADENOSINE - A NEWER PURINE ANALOG ACTIVE IN THE TREATMENT OF INDOLENT LYMPHOID MALIGNANCIES
SAVEN, A
PIRO, LD
[J]. ANNALS OF INTERNAL MEDICINE, 1994, 120 (09) : 784 - 791
[9] 2-CHLORODEOXYADENOSINE-INDUCED COMPLETE REMISSIONS IN LANGERHANS-CELL HISTIOCYTOSIS
SAVEN, A
FOON, KA
PIRO, LD
[J]. ANNALS OF INTERNAL MEDICINE, 1994, 121 (06) : 430 - 432
[10] CLADRIBINE IN TREATMENT OF CHRONIC PROGRESSIVE MULTIPLE-SCLEROSIS
SIPE, JC
ROMINE, JS
KOZIOL, JA
MCMILLAN, R
ZYROFF, J
BEUTLER, E
[J]. LANCET, 1994, 344 (8914) : 9 - 13

← 1 2 →