Absorption potential and its variants

被引:8
作者
Boxenbaum, H [1 ]
机构
[1] Arishel Inc, N Potomac, MD 20878 USA
关键词
oral drug absorption; dose-solubility complex; partition coefficient; fraction available to the liver;
D O I
10.1023/A:1011934929070
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:1893 / 1893
页数:1
相关论文
共 5 条
[1]   A THEORETICAL BASIS FOR A BIOPHARMACEUTIC DRUG CLASSIFICATION - THE CORRELATION OF IN-VITRO DRUG PRODUCT DISSOLUTION AND IN-VIVO BIOAVAILABILITY [J].
AMIDON, GL ;
LENNERNAS, H ;
SHAH, VP ;
CRISON, JR .
PHARMACEUTICAL RESEARCH, 1995, 12 (03) :413-420
[2]   ABSORPTION POTENTIAL - ESTIMATING THE FRACTION ABSORBED FOR ORALLY-ADMINISTERED COMPOUNDS [J].
DRESSMAN, JB ;
AMIDON, GL ;
FLEISHER, D .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1985, 74 (05) :588-589
[3]   Guidance in the setting of drug particle size specifications to minimize variability in absorption [J].
Johnson, KC ;
Swindell, AC .
PHARMACEUTICAL RESEARCH, 1996, 13 (12) :1795-1798
[4]  
*SPSS INC, 1995, TABL 3D WIND
[5]   In vitro permeability across Caco3 cells (colonic) can predict in vivo (small intestinal) absorption in man - Fact or myth [J].
Yee, SY .
PHARMACEUTICAL RESEARCH, 1997, 14 (06) :763-766