Absorption potential and its variants

被引：8

作者：

Boxenbaum, H ^{[1
]}

机构：

[1] Arishel Inc, N Potomac, MD 20878 USA

来源：

PHARMACEUTICAL RESEARCH | 1999年 / 16卷 / 12期

关键词：

oral drug absorption; dose-solubility complex; partition coefficient; fraction available to the liver;

D O I：

10.1023/A:1011934929070

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

收藏

页码：1893 / 1893

页数：1

相关论文

共 5 条

[1] A THEORETICAL BASIS FOR A BIOPHARMACEUTIC DRUG CLASSIFICATION - THE CORRELATION OF IN-VITRO DRUG PRODUCT DISSOLUTION AND IN-VIVO BIOAVAILABILITY [J].

AMIDON, GL ;

LENNERNAS, H ;

SHAH, VP ;

CRISON, JR .

PHARMACEUTICAL RESEARCH, 1995, 12 (03) :413-420

[2] ABSORPTION POTENTIAL - ESTIMATING THE FRACTION ABSORBED FOR ORALLY-ADMINISTERED COMPOUNDS [J].

DRESSMAN, JB ;

AMIDON, GL ;

FLEISHER, D .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1985, 74 (05) :588-589

[3] Guidance in the setting of drug particle size specifications to minimize variability in absorption [J].

Johnson, KC ;

Swindell, AC .

PHARMACEUTICAL RESEARCH, 1996, 13 (12) :1795-1798

[4]

*SPSS INC, 1995, TABL 3D WIND

[5] In vitro permeability across Caco3 cells (colonic) can predict in vivo (small intestinal) absorption in man - Fact or myth [J].

Yee, SY .

PHARMACEUTICAL RESEARCH, 1997, 14 (06) :763-766