A novel method for separating the anodic voltammetric peaks of dopamine and ascorbic acid

被引：33

作者：

Gu, HY

Xu, Y

Peng, WL

Li, GX ^{[1
]}

Chen, HY

机构：

[1] Nanjing Univ, Dept Biochem, Nanjing 210093, Peoples R China

[2] Nanjing Univ, Natl Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China

[3] Nantong Med Coll, Jiangsu Province Key Lab Neuroregenerat, Dept Hygeian Analyt Chem, Nantong 226001, Peoples R China

[4] Nanjing Univ, Dept Chem, Inst Analyt Sci, Nanjing 210093, Peoples R China

来源：

MICROCHIMICA ACTA | 2004年 / 146卷 / 3-4期

关键词：

dopamine; ascorbic acid; voltammetric separation;

D O I：

10.1007/s00604-003-0177-z

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This paper presents a simple and reliable method for separating the anodic peaks of dopamine (DA) and ascorbic acid (AA). Good electrochemical responses of DA and AA can be obtained at an electrochemically pretreated glassy carbon electrode (PGCE). The electrode reaction of DA is a quasi-reversible process, but the oxidation of AA is entirely irreversible. Consequently, the PGCE can be used to separate the anodic peaks of DA and AA. The separation can be higher than 290 mV, and the detection limit (S/N=3) of DA is 6.0x10(-8) M. This PGCE is very stable and can be used for as long as four weeks.

引用

收藏

页码：223 / 227

页数：5

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