CD137: costimulator turns suppressor?

被引:4
作者
Al-Shamkhani, A [1 ]
机构
[1] Univ Southampton, Sch Med, Canc Sci Div, Tenovus Res Lab, Southampton SO16 6YD, Hants, England
关键词
CD137; costimulator; immunotherapy; suppressor;
D O I
10.1111/j.1365-2567.2004.01963.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:23 / 25
页数:3
相关论文
共 33 条
[1]   CRYSTAL-STRUCTURE OF THE SOLUBLE HUMAN 55 KD TNF RECEPTOR-HUMAN TNF-BETA COMPLEX - IMPLICATIONS FOR TNF RECEPTOR ACTIVATION [J].
BANNER, DW ;
DARCY, A ;
JANES, W ;
GENTZ, R ;
SCHOENFELD, HJ ;
BROGER, C ;
LOETSCHER, H ;
LESSLAUER, W .
CELL, 1993, 73 (03) :431-445
[2]   A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo [J].
Bertram, EM ;
Dawicki, W ;
Sedgmen, B ;
Bramson, JL ;
Lynch, DH ;
Watts, TH .
JOURNAL OF IMMUNOLOGY, 2004, 172 (02) :981-988
[3]   Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection [J].
Bertram, EM ;
Lau, P ;
Watts, TH .
JOURNAL OF IMMUNOLOGY, 2002, 168 (08) :3777-3785
[4]   A two-step, two-signal model for the primary activation of precursor helper T cells [J].
Bretscher, PA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (01) :185-190
[5]   Co-stimulatory members of the TNFR family: Keys to effective T-cell immunity? [J].
Croft, M .
NATURE REVIEWS IMMUNOLOGY, 2003, 3 (08) :609-620
[6]   Expression and function of 4-1BB during CD4 versus CD8 T cell responses in vivo [J].
Dawicki, W ;
Watts, TH .
EUROPEAN JOURNAL OF IMMUNOLOGY, 2004, 34 (03) :743-751
[7]   CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice [J].
Foell, J ;
Strahotin, S ;
O'Neil, SP ;
McCausland, MM ;
Suwyn, C ;
Haber, M ;
Chander, PN ;
Bapat, AS ;
Yang, XJ ;
Chiorazzi, N ;
Hoffmann, MK ;
Mittler, RS .
JOURNAL OF CLINICAL INVESTIGATION, 2003, 111 (10) :1505-1518
[8]   Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance [J].
Foell, JL ;
Diez-Mendiondo, BI ;
Diez, OH ;
Holzer, U ;
Ruck, P ;
Bapat, AS ;
Hoffmann, MK ;
Mittler, RS ;
Dannecker, GE .
IMMUNOLOGY, 2004, 113 (01) :89-98
[9]   Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells [J].
Futagawa, T ;
Akiba, H ;
Kodama, T ;
Takeda, K ;
Hosoda, Y ;
Yagita, H ;
Okumura, K .
INTERNATIONAL IMMUNOLOGY, 2002, 14 (03) :275-286
[10]   In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses [J].
Halstead, ES ;
Mueller, YM ;
Altman, JD ;
Katsikis, PD .
NATURE IMMUNOLOGY, 2002, 3 (06) :536-541