Colonization dynamics of altered Schaedler flora is influenced by gender, aging, and Helicobacter hepaticus infection in the intestines of Swiss Webster mice

被引：42

作者：

Ge, Zhongming

Feng, Yang

Taylor, Nancy S.

Ohtani, Masahiro

Polz, Martin F.

Schauer, David B.

Fox, James G.

机构：

[1] MIT, Div Comparat Med, Cambridge, MA 02139 USA

[2] MIT, Dept Civil & Environm Engn, Cambridge, MA 02139 USA

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2006年 / 72卷 / 07期

关键词：

GASTROINTESTINAL MICROFLORA; MICROBIOTA; BACTERIA; DISEASE; MUCOSA; TRACT; PCR;

D O I：

10.1128/AEM.01934-05

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The distribution and colonization levels of the altered Schaedler flora (ASF) in their natural hosts are poorly understood. Intestinal colonization levels of the eight ASF strains in outbred Swiss Webster mice with or without Helicobacter hepaticus infection were characterized by real-time quantitative PCR. All ASF strains were detected in the cecum and colon, but some strains displayed significant variation in colonization levels with host age, gender, and H. hepaticus infection status.

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收藏

页码：5100 / 5103

页数：4

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