Evaluation of the mutagenicity and antimutagenicity of extracts from oat, buckwheat and wheat bran in the Salmonella/microsome assay

被引：14

作者：

Brindzova, Lucia ^{[1
]}

Mikulasova, Maria ^{[3
]}

Takacsova, Maria ^{[1
]}

Mosovska, Silvia ^{[1
]}

Opattova, Alena ^{[2
]}

机构：

[1] Slovak Tech Univ, Dept Nutr & Food Evaluat, Fac Chem & Food Technol, Bratislava 81237, Slovakia

[2] Slovak Tech Univ, Dept Biochem & Microbiol, Fac Chem & Food Technol, Bratislava 81237, Slovakia

[3] Comenius Univ, Inst Cell Biol, Bratislava, Slovakia

来源：

JOURNAL OF FOOD COMPOSITION AND ANALYSIS | 2009年 / 22卷 / 01期

关键词：

Cereals; Pseudocereals; Antimutagenic activity; Phenolic compounds; Food composition; ANTIOXIDANT ACTIVITY; PHENOLIC-COMPOUNDS; TEA EXTRACTS; GREEN TEA; FRUITS; ACIDS;

D O I：

10.1016/j.jfca.2008.07.009

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

This Study examined the mutagenic and antimutagenic activities of the DMSO extracts front the oat, buckwheat and wheat bran, which are good sources of polyphenols with antioxidant and anticarcinogenic properties. Extracts from buckwheat and wheat bran showed no mutagenic activity. Oat extract showed slight mutagenic effect in Salmonella typhimurium TA102. The antimutagenic activities against direct-acting (3-(5-nitro-2-furyl)acrylic acid, 2-nitrofluorene, hydrogen peroxide) and indirect-acting(aflatoxin B1) mutagens were also investigated using Ames test with S. typhimurium TA98, TA100 and TA102. Cereal extracts exhibit concentration-dependent protective antigenotoxic activity against all Used mutagens. The total phenolic content ill Studied cereal extracts expressed as gallic acid equivalent increases in the order: buckwheat < wheat bran < oat. Total flavonoid content expressed as rutin equivalent increases in the order: oat < wheat bran < buckwheat. (C) 2008 Elsevier Inc., All rights reserved.

引用

页码：87 / 90

页数：4

共 27 条

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