Nucleophilic vinylic substitutions of (E)- and (Z)-ethyl 3-aryl-3-chloro-2-cyanopropenoates with primary and secondary amines

被引：6

作者：

Jalander, LF

Lonnqvist, JE

机构：

[1] Department of Organic Chemistry, Åbo Akademi, Fin-20500 Åbo

来源：

SYNTHETIC COMMUNICATIONS | 1996年 / 26卷 / 19期

关键词：

D O I：

10.1080/00397919608003764

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Some new (Z)-ethyl 3-amino-3-aryl-2-cyanopropenoates have been prepared in good yields by reacting (E)- and (Z)-ethyl 3-aryl-3-chloro-2-cyanopropenoates with primary and secondary amines. The (Z)-isomers were exclusively formed although the starting material consisted of a mixture of (E)- and (Z)-isomers (approximate to 1:1)

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页码：3549 / 3557

页数：9

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