A novel integron in Salmonella enterica serovar enteritidis, carrying the blaDHA-1 gene and its regulator gene ampR, originated from Morganella morganii

被引:84
作者
Verdet, C
Arlet, G
Barnaud, G
Lagrange, PH
Philippon, A
机构
[1] Hop Tenon, Serv Bacteriol, F-75970 Paris 20, France
[2] Hop Lariboisiere, Serv Bacteriol, F-75475 Paris, France
[3] Hop St Louis, Microbiol Serv, Paris, France
[4] Hop Cochin, Serv Bacteriol, F-75674 Paris, France
关键词
D O I
10.1128/AAC.44.1.222-225.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The genetic organization of the gene coding for DHA-1 and the corresponding ampR gene was determined by PCR mapping. These genes have been mobilized from the Morganella morganii chromosome and inserted into a complex sulI-type integron, similar to In6 and In7. However, they are not themselves mobile cassettes. This integron probably includes a specific site for recombination allotting the mobilization of diverse resistance genes, as observed for bla(CMY-1) and bla(MOX-1).
引用
收藏
页码:222 / 225
页数:4
相关论文
共 18 条
  • [1] ALTSCHUL SF, 1990, J MOL BIOL, V215, P403, DOI 10.1006/jmbi.1990.9999
  • [3] A NOVEL INTEGRON-LIKE ELEMENT CARRYING THE METALLO-BETA-LACTAMASE GENE BLA(IMP)
    ARAKAWA, Y
    MURAKAMI, M
    SUZUKI, K
    ITO, H
    WACHAROTAYANKUN, R
    OHSUKA, S
    KATO, N
    OHTA, M
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (07) : 1612 - 1615
  • [4] Cloning and sequencing of the gene encoding the AmpC beta-lactamase of Morganella morganii
    Barnaud, G
    Arlet, G
    Danglot, C
    Philippon, A
    [J]. FEMS MICROBIOLOGY LETTERS, 1997, 148 (01) : 15 - 20
  • [5] Salmonella enteritidis:: AmpC plasmid-mediated inducible β-lactamase (DHA-1) with an ampR gene from Morganella morganii
    Barnaud, G
    Arlet, G
    Verdet, C
    Gaillot, O
    Lagrange, PH
    Philippon, A
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (09) : 2352 - 2358
  • [6] Comparative characterization of the cephamycinase bla(CMY-1) gene and its relationship with other beta-lactamase genes
    Bauernfeind, A
    Stemplinger, I
    Jungwirth, R
    Wilhelm, R
    Chong, Y
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (08) : 1926 - 1930
  • [7] RIBOSOMAL RIBONUCLEIC-ACID GENE RESTRICTION PATTERNS AS POTENTIAL TAXONOMIC TOOLS
    GRIMONT, F
    GRIMONT, PAD
    [J]. ANNALES DE L INSTITUT PASTEUR-MICROBIOLOGIE, 1986, 137B (02): : 165 - 175
  • [8] INTEGRONS FOUND IN DIFFERENT LOCATIONS HAVE IDENTICAL 5' ENDS BUT VARIABLE 3' ENDS
    HALL, RM
    BROWN, HJ
    BROOKES, DE
    STOKES, HW
    [J]. JOURNAL OF BACTERIOLOGY, 1994, 176 (20) : 6286 - 6294
  • [9] MOBILE GENE CASSETTES AND INTEGRONS - CAPTURE AND SPREAD OF GENES BY SITE-SPECIFIC RECOMBINATION
    HALL, RM
    COLLIS, CM
    [J]. MOLECULAR MICROBIOLOGY, 1995, 15 (04) : 593 - 600
  • [10] CHARACTERIZATION OF A PLASMID-BORNE AND CONSTITUTIVELY EXPRESSED BLA(MOX-1) GENE ENCODING AMPC-TYPE BETA-LACTAMASE
    HORII, T
    ARAKAWA, Y
    OHTA, M
    SUGIYAMA, T
    WACHAROTAYANKUN, R
    ITO, H
    KATO, N
    [J]. GENE, 1994, 139 (01) : 93 - 98