Cardiovascular and endocrine effects of acupuncture in hypertensive patients

被引:71
作者
Chiu, YJ [1 ]
Chi, A [1 ]
Reid, IA [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO,DEPT PHYSIOL,SAN FRANCISCO,CA
关键词
acupuncture; renin; vasopressin; cortisol; blood pressure; hypertension;
D O I
10.3109/10641969709083204
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
It has been reported that acupuncture can decrease blood pressure in patients with hypertension, possibly by an endocrine mechanism. The aim of the present study was to investigate the effects of acupuncture on arterial blood pressure and the secretion of renin, vasopressin and cortisol in hypertensive patients. Acupuncture was performed in fifty untreated essential hypertensive patients resting in the supine position. Thirty min after acupuncture there were decreases in systolic pressure from 169 +/- 2 to 151 +/- 2 mm Hg, diastolic pressure from 107 +/- 1 to 96 +/- 1 mm Hg, and heart rate from 77 +/- 2 to 72 +/- 2 bpm (P<0.01). Plasma renin activity decreased from 1.7 +/- 0.4 to 1.1 +/- 0.2 ng/ml/2h (P<0.01), but there were no significant changes in plasma vasopressin or cortisol concentrations. These results confirm that acupuncture decreases blood pressure in hypertensive patients, and suggest that the decrease results, at least in part, from a decrease in renin secretion.
引用
收藏
页码:1047 / 1063
页数:17
相关论文
共 27 条
[1]   STRESS HORMONES - THEIR INTERACTION AND REGULATION [J].
AXELROD, J ;
REISINE, TD .
SCIENCE, 1984, 224 (4648) :452-459
[2]  
Chen G, 1975, Am J Chin Med (Gard City N Y), V3, P27, DOI 10.1142/S0192415X75000049
[3]   ADRENAL CORTICOSTEROID SYNTHESIS AND HYPERTENSION [J].
CONNELL, JMC ;
FRASER, R .
JOURNAL OF HYPERTENSION, 1991, 9 (02) :97-107
[4]   MECHANISMS REGULATING RENIN RELEASE [J].
DAVIS, JO ;
FREEMAN, RH .
PHYSIOLOGICAL REVIEWS, 1976, 56 (01) :1-56
[5]   PRESSOR SYSTEMS IN HYPERTENSION AND CONGESTIVE-HEART-FAILURE - ROLE OF VASOPRESSIN [J].
GAVRAS, H ;
FITZ, A ;
BRODY, M ;
HAJDUCZOK, G ;
MARK, A ;
LAWTON, W ;
CHAPLEAU, M .
HYPERTENSION, 1990, 16 (05) :587-593
[6]   PSYCHOSOCIAL MECHANISMS OF PRIMARY HYPERTENSION [J].
HENRY, JP ;
GRIM, CE .
JOURNAL OF HYPERTENSION, 1990, 8 (09) :783-793
[7]  
KEETON TK, 1980, PHARMACOL REV, V32, P81
[8]   REDUCTION IN PLASMA VASOPRESSIN LEVELS OF DEHYDRATED RATS FOLLOWING ACUTE STRESS [J].
KEIL, LC ;
SEVERS, WB .
ENDOCRINOLOGY, 1977, 100 (01) :30-38
[9]  
KHO HG, 1993, EUR J ANAESTH, V10, P197
[10]  
LARAGH JH, 1995, HYPERTENSION PATHOPH