Aqueous Copper- Mediated Living Radical Polymerisation of N - Acryloylmorpholine, SET- LRP in Water

被引：57

作者：

Anastasaki, Athina ^{[1
]}

Haddleton, Alice J. ^{[1
]}

Zhang, Qiang ^{[1
]}

Simula, Alexandre ^{[1
]}

Droesbeke, Martijn ^{[1
]}

Wilson, Paul ^{[1
]}

Haddleton, David M. ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2014年 / 35卷 / 10期

关键词：

ATRP; biocompatible; living radical polymerisation; poly(N-acryloylmorpholine); SET-LRP; POLYETHYLENE-GLYCOL CONJUGATION; AMPHIPHILIC BLOCK-COPOLYMERS; RAFT POLYMERIZATION; EXCHANGE-TRANSFUSION; METHYL-METHACRYLATE; BOVINE HEMOGLOBIN; METALLIC COPPER; MOLECULAR-WEIGHT; BUILDING-BLOCKS; GLYCOPOLYMERS;

D O I：

10.1002/marc.201400024

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The polymerisation of N-acryloylmorpholine in water is reported utilising Cu(0)-mediated living radical polymerisation (SET-LRP). The inherent instability of [Cu-I(Me-6-Tren)Br] in aqueous solution is exploited via rapid disproportionation to prepare Cu(0) particles and [Cu-II(Me-6-Tren)Br-2] in situ prior to addition of monomer and initiator. Quantitative conversion is attained within 30 min for various degrees of polymerisation (DPn = 20-640) with SEC showing symmetrical narrow molecular weight distributions (D < 1.18) in all cases. Optimised conditions are subsequently applied for the preparation of a diblock copolymer poly(NIPAm)-b-(N-acryloylmorpholine), illustrating the versatility of this approach.

引用

页码：965 / 970

页数：6

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