New On-Bead Near-Infrared Fluorophores and Fluorescent Sensor Constructs

被引:89
作者
Palma, Aniello [1 ]
Tasior, Mariusz [1 ]
Frimannsson, Daniel O. [1 ]
Vu, Thanh Truc [2 ]
Meallet-Renault, Rachel [2 ]
O'Shea, Donal F. [1 ]
机构
[1] Univ Coll Dublin, Ctr Synth & Chem Biol, Sch Chem & Chem Biol, Dublin 4, Ireland
[2] CNRS, ENS Cachan, PPSM, F-94230 Cachan, France
基金
爱尔兰科学基金会;
关键词
CHEMOSENSOR; STRATEGY; DESIGN;
D O I
10.1021/ol901413u
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The facile synthesis and photophysical characterization of new on-bead fluorophores and fluorescent sensors are described. The unique covalent immobilization strategy results in highly fluorescent beads with sharp emission profiles between 650 and 800 nm. Illustrative examples include imaging In an aqueous cellular environment and adaptation to include off/on sensing functionality, proven by a prototypical detection of gaseous HCI.
引用
收藏
页码:3638 / 3641
页数:4
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